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Mouse Angptl4 (Farp) (Fiaf) (Ng27) (a.a. 24-410)

Angptl4 Swiss Prot#

Q9Z1P8

Angptl4 Protein names

Angiopoietin-related protein 4 (Angiopoietin-like 4) (Hepatic

fibrinogen/angiopoietin-related protein) (HFARP) (Fasting-induced adipose

factor) (Secreted protein Bk89) (425O18-1)

Angptl4 Gene names

Angptl4 (Farp) (Fiaf) (Ng27)

Organism

Mouse

Angptl4 Entry name

ANGL4_MOUSE

Angptl4 Codon optimized cDNA Clone

Angptl4 CDNA Cat#

RPE0345

cDNA Tag

cDNA Angptl4 Contains A 6x histidine tag

Condon optimized Angptl4 CDNA Formulation

Liquid

Condon optimized Angptl4 CDNA Storage

Ship at Room temperature. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

Condon optimized Angptl4 cDNA Applications

Applications: 1. Codon-optimized cDNA sequence designed for recombinant

protein production in both E.coli and Mammalian cell. The cDNA has been

cloned into E.coli expression vector with 6x Histidine tag.2. May be used as

RNAi assistance to restore the loss-of-function.

Recombinant Angptl4 Protein

Recombinant Angptl4 Protein Cat#

PE0345

Angptl4 Protein Source

Recombinant protein.

Recombinant Angptl4 Protein Applications

Western Blot, may be used for other applications determined by user

Recombinant Angptl4 Protein Purity

>90%, as determined by SDS-PAGE under reducing conditions

Recombinant Angptl4 Protein Activity

N/A

Recombinant protein Tag

Recombinant Angptl4 contains A 6x histidine tag

Recombinant Angptl4 Protein Formulation

Liquid

Recombinant Angptl4 Protein Storage

Ship at 4℃. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw

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Angptl4 Protein family

Angptl4 Subcellular locations

Secreted. Secreted > extracellular space > extracellular matrix.

Angptl4 FUNCTION (According to UniProtKB/Swiss Prot)

FUNCTION: Protein with hypoxia-induced expression in endothelial cells.

May act as a regulator of angiogenesis and modulate tumorgenesis. Inhibits

proliferation, migration, and tubule formation of endothelial cells and

reduces vascular leakage. May exert a protective function on endothelial

cells through an endocrine action. It is directly involved in regulating

glucose homeostasis, lipid metabolism, and insulin sensitivity (By

similarity). In response to hypoxia, the unprocessed form of the protein

accumulates in the subendothelial extracellular matrix (ECM). The matrix-

associated and immobilized unprocessed form limits the formation of actin

stress fibers and focal contacts in the adhering endothelial cells and

inhibits their adhesion. It also decreases motility of endothelial cells and

inhibits the sprouting and tube formation.

Angptl4 Sequence databases

EMBL

DDBJ

GenBank

Angptl4 3D structure databases

ModBase

Angptl4 Protein-protein interaction databases

STRING

Angptl4 Proteomic databases

PRIDE

Angptl4 Genome annotation databases

Ensembl

GeneID

KEGG

UCSC

Angptl4 Organism specific databases

CTD

MGI

Angptl4 Phylogenomic databases

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Angptl4 Gene expression databases

Bgee

ArrayExpress

Genevestigator

Angptl4 Family and domain databases

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY