BcMag™ DVS-Activated Magnetic Beads are pre-activated, uniform, silica-based superparamagnetic beads coated with high density DVS (Divinyl Sulfone) functional groups on the surface. The beads are used to covalently conjugate primary amino, sulfhydryl, or hydroxyl groups-containing ligands (Fig.1). BcMag™ DVS-Activated Magnetic Beads are ideal matrix for immobilizing larger molecules and small peptides because the long-arm (15-atom) hydrophilic linker may reduce steric hindrance.
Features and Advantages:
Pre-activated and ready-to-use
Recommended coupling conditions: pH 6-10, 4-25°C, 2–24 h.
Stable covalent bond with minimal ligand leakage
Produces reusable immunoaffinity matrices
Low nonspecific binding
Immobilize 1-10 mg protein or 0.1-1 mg peptide/ml beads